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S.E.M.I. – Side Effects May Include...
#3957560S.E.M.I. is a single-player and co-op action platformer with puzzle elements. Play as patients of an unusual clinic, take experimental drugs, interfere with each other, and be ready for chaos and unpredictable side effects!
Recommendation
ProtonGreat
CurrentLow confidence
Only Proton reports exist so far.
Last report Apr 9, 2026
Compatibility
Proton
Great
CurrentLow confidence
2 reports · Low confidence: very few recent reports yet.
NativeNone
No native Linux build — Proton only
Anti-cheatUnknown
No anti-cheat reports yet
Reports(2)
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